| Customization: | Available |
|---|---|
| CAS No.: | 987-78-0 |
| Formula: | C14h25n4o11p2 |
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Citicoline sodium(C14H25N4NaO11P2) |
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CAS |
987-78-0 |
|
Appearance |
White powder |
|
Purity |
≥99.0% |
|
Loss on drying |
Not more than 6% |
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Heavy Metal |
Not more than 5ppm |
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Application |
Raw material, medicine |
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Shelf Life |
24 months when properly stored. |
| Molecular weight | 488.324 |
| Application | Pharma supplement ingredients |
What's Citicoline?
Citicoline (alternatively known as cytidine diphosphate-choline or CDP-choline) is a naturally occurring substance found in every cell of the body that plays an essential role in the maintenance of cell membrane structure and function. Citicoline has been approved in numerous countries around the world for various applications, including the management of stroke-induced cognitive decline and age-related memory decline. Citicoline has also been studied in people following work-related head injuries, career burnout recovery, and for the overall management of Alzheimer's disease, though these last two uses remain largely unapproved in many countries.
Citicoline is a precursor for the production of acetylcholine (ACh) - a neurotransmitter which plays a key role in cognitive functions, including memory and learning. Citicoline increases ACh levels, which helps improve cognition and focus. For example, as a stroke survivor, aging person or someone with cognitive decline, taking citicoline may help improve one's ability to remember what happened during the day, complete tasks more accurately or efficiently, and stay on-task or alert over a period of time.
Citicoline is also an antioxidant that has been shown to neutralize acetylcholine and dopamine which can cause excessive oxidation in brain tissues. Oxidative stress and free radical damage can damage cells and disrupt metabolic processes, leading to cell death. The antioxidant activity of citicoline has been studied extensively and has been linked to reduced oxidative damage, improved cell health and better overall functioning.
Function of Citicoline
Citicoline can be used for the management of stroke, transient ischemic attack, and age-related cognitive decline associated with aging. It is also used to support cognitive functions, preserve cognitive performance and decrease the risk of cognitive decline in the aging population. It has demonstrated the ability to facilitate recovery in stroke patients, reduce the risk of stroke recurrence, and improve various physical and mental functions including consciousness, mental alertness, memory, motor function, and attention.
Citicoline is most often utilized for the management of Alzheimer's disease and cognitive decline associated with aging. It has demonstrated the ability to improve cognitive scores, including Mini Mental State Examination (MMSE) scores, Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) scores, and Modified Hasegawa's dementia rating scale scores, in the elderly population. It can also improve overall functionality, including the ability to engage in activities of daily living.
It has also been studied in the areas of substance abuse and mental health, with research showing potential positive effects on symptoms of nicotine addiction, schizophrenia, depression and anxiety.
Citicoline is also used to prevent and treat fatty liver, reduce the effects of alcohol on the liver, and may help improve liver function for those diagnosed with cirrhosis. Citicoline can also be beneficial for those suffering from tinnitus.
Overall, citicoline is a promising treatment for a variety of cognitive, physical, and mental health conditions. It is relatively non-toxic and well tolerated and can be used for the management of stroke, cognitive decline, substance abuse, and tinnitus.
Package detail:1-5kg/aluminum foil bag; 20/25Kgs in drum with two PE bags inside, support packing OEM
We offer free samples ranging from 10-30g for testing purposes if you find our prices suitable and our product meets your requirements. However, the buyer is responsible for covering the freight costs. Our samples are securely packed in PE/Aluminum Foil Bags for safe transportation. Additionally, we provide a Certificate of Analysis (COA) for the batch within three months.
1. Assay customization
Regular: more than 98%
High assay: more than 99%
Low assay: specified assay+specified auxiliary materials
2. Density Customization
Regular: about 0.35g/ml
High density: more than 0.45g/ml
Low density: less than 0.3g/ml
3. Mesh customization
Regular: 100 mesh
Good liquidity: 20-80 mesh
Strong graininess: 40-60 mesh
GSH BIO-TECH is an innovative high-tech enterprise with the core of enzyme catalysis technology in the field of synthetic biology and the interdisciplinary application of multidisciplinary technology. The aim is to develop biotechnology and industrialize high-value-added API. The pioneer of the global enzymatic catalyzed coupled ATP regeneration technology, we advocate green production and have been committed to providing customers with better and more environmentally friendly products and services. As a powerful production-oriented enterprise, we truly integrate R&D, production and sales, with stable supply and quality for customers and double guarantee of service.
The company's main products are L-glutathione reduced (GSH), β-Nicotinamide Mononucleotide (NMN), Citicoline Sodium (CDPC) and other raw materials. The acid market share ranks among the top three in China, and the products are exported to Europe, America, South Korea, India and other parts of the world.
1. R&D CENTER:
Beijing Tiankaiyida Bio-Technology Co.,LTD.
The company R&D center is located in Beijing Fengtai Science and Technology Park, with complete molecular biology, synthetic biology and fermentation laboratories. The R&D team is composed of well-known domestic universities and personnel studying in the United States and Germany. The company's research and development of GSH, NMN and other production technologies are internationally leading, all of which are self-developed enzymatic technology and have obtained a number of national patents. Meanwhile, we have also applied for various product certificates, such as KOSHER, HALAL, ISO9001, FDA, HACCP, BRC, etc.
2. PRODUCTION BASES:
The factory is designed and constructed in accordance with GMP requirements, and production and operation comply with EUGMP requirements.
Anhui GSH production base: It covers an area of 20,000 m2, has a construction area of 10,000 m2, invested 120 million in production equipment and 20 million in safety and environmental protection. Annual capaticy of GSH can reach around 200tons.
Jilin Aoteng production base: Annual capaticy of GSH is 70tons, GMP standard plant, strict quality control system.
Jilin GSH production base: It's our third factory, located in Yanbian "West Gate"-- Jilin Dunhua. The new plant, with an investment of 580 million yuan, will cover an area of 62,000 square meters and a construction area of 33,000 square meters. It will mainly build standard fermentation workshops, reaction workshops, purification workshops and crystallization workshops, as well as raw materials, product warehouse. It is estimated that during the 14th five-year plan period, the annual capaticy of NMN will be over 1000 tons.
3. MARKET HEADQUARTER: Shenzhen GSH Bio-Technology Co.,LTD.
>Our product is produce based on USP41, EP and CP standard.
>100% QC in produce process and before package.
>We are certified manufacturer with ISO9001,KOSHER,HALAL,FDA.
> 25kg/drum with 2 plastic bags inside, or 1kg/aluminum foil bag and customized is accept.
>Yes, we usually provide 30-100g free sample for you to testing quality.
>We accept T/T in advance, L/C at sight.
>Delivery will be in 3-5 day once received payment.
>We cooperate with Fedex ,UPS, and shipping can by Air/Sea.
>Yes, our annual capacity is 20-50 tons and we have warehouse to assure the supplying on time.
>Usually we quote within 24 hours after we get your inquiry.
>The free sample is ready for delivery in 1-3 days. The samples will be sent to you via express and arrive in 3-5 days.
>We accept EXW, FOB, CFR, CIF, etc. You can choose the one which is the most convenient or cost effective for you.
>Usually 100% T/T in advance.
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